Zoledronic Acid Regulates Autophagy and Induces Apoptosis in Colon Cancer Cell Line CT26
نویسندگان
چکیده
منابع مشابه
Zoledronic Acid Regulates Autophagy and Induces Apoptosis in Colon Cancer Cell Line CT26
Zoledronic acid (ZOL) is the third generation of bisphosphonates, which can inhibit many tumors growth, especially to inhibit the growth of colon cancer. However, the molecular mechanism is still very mysterious. In this study, we observed that ZOL could regulate CT26 colon cancer cells autophagy, promote CT26 cells apoptosis, and inhibit CT26 cells proliferation. Western blotting analysis show...
متن کاملGallic Acid Inhibits Proliferation and Induces Apoptosis in Lymphoblastic Leukemia Cell Line (C121)
AbstractLeukemia is known as the world’s fifth most prevalent cancer. New cytotoxic drugs have created considerable progress in the treatment, but side effects are still the important cause of mortality. Plant derivatives have been recently considered as important sources for the treatment of various diseases, including cancer. Gallic acid (GA) is a polyhydroxyphenolic compound with a wide rang...
متن کاملElephantopus scaber Linn Extract Induces Apoptosis And Activate Caspase Cascade In T47d Cancer Cell Line
Elephantopus scaber Linn. was used traditionally for treating various diseases. Previous studies found the cytotoxicity of this herb against different cell lines. This study aimed to determine the effectiveness of the ethanolic extract of E.scaber in inducing apoptosis by observing itseffect on caspase cascade. This ethanolic extract was obtained by maceration method using 96% ethanol. It was f...
متن کاملApatinib has anti-tumor effects and induces autophagy in colon cancer cells
Objective(s): Apatinib recently has been used to treat patients with gastric cancer, but the function of apatinib in colon cancer remains unclear. This study was conducted to investigate the impacts of apatinib on the biological function and its potential mechanism of colon cancer cells in vitro. Materials and Methods:The effect of apatinib in colon cancer cells were detected by assessing cell ...
متن کاملSynergistic effects of Radiofrequency Hyperthermia temperature rate with magnetic Graphene oxide nanoparticles drug targeting on CT26 colon cancer cell line
Introduction: Graphene oxide (GO) sheets are carbon-networking nanomaterials offering excellent potential for drug delivery platforms due to hydrophobic interactions and high drug-loading efficiency. Superparamagnetic iron oxide nanoparticles can be used in certain applications such as cell labeling, drug delivery, targeting, magnetic resonance imaging and hyperthermia. Due t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BioMed Research International
سال: 2017
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2017/7203584